Guide round home, a turn up for the book (6)
I believe the answer is:
daniel
'the book' is the definition.
(I've seen this before)
'guide round home a turn up' is the wordplay.
'guide' becomes 'lead' (synonyms).
'round' means one lot of letters goes inside another.
'home' becomes 'in' ('he's home' can mean 'he's in').
'a turn up' says the letters should be written backwards.
'lead' enclosing 'in' is 'leinad'.
'leinad' reversed gives 'DANIEL'.
'for' is the link.
(Other definitions for daniel that I've seen before include "Hebrew prophet saved from the lions' den" , "Biblical prophet thrown into the lion's den" , "-- Barenboim, conductor/pianist" , "Sandinista leader" , "Book of the Bible; man's name" .)