Guile Poe affected for concluding speech (8)
I believe the answer is:
epilogue
'concluding speech' is the definition.
'epilogue' can be an answer for 'speech' (I have seen 'dramatic speech' mean 'epilogue' so perhaps 'speech' could also mean 'epilogue'). I'm unsure of the 'concluding' bit.
'guile poe affected' is the wordplay.
'affected' indicates anagramming the letters.
'guile'+'poe'='guilepoe'
'guilepoe' is an anagram of 'EPILOGUE'.
'for' is the link.
Can you help me to learn more?
(Other definitions for epilogue that I've seen before include "End part of book, play" , "Short passage added at the end of a literary work" , "Concluding section of book, play, etc" , "dramatic speech" , "Closing speech (in play)" .)