H2O (5)

I believe the answer is:

water

'h2o' is the definition.
(synonyms)

This is the entire clue.

(Other definitions for water that I've seen before include "Commonest liquid" , "Irrigate" , "Lake or river" , "What can produce solution" , "Commonplace drink" .)

I've seen this clue in The Telegraph, the USA Today and The Irish Times.

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