Hairstyle from which queen rarely departs? (7)
I believe the answer is:
beehive
This clue is a double definition.
'hairstyle' is the first definition.
(beehive is a kind of hairstyle)
'from which queen rarely departs?' is the second definition.
(as in a queen bee)
(Other definitions for beehive that I've seen before include "place of business" , "Enclosure where honey is first made" , "hair style" , "Source of combs" , "Home to a queen" .)