Half of these detest labour resulting in deviation from directions given (6)
I believe the answer is:
detour
'deviation from directions given' is the definition.
'detour' can be an answer for 'deviation' (I've seen this before). I am not sure about the 'from directions given' bit.
'half of these detest labour' is the wordplay.
'half of' indicates taking half.
'these detest' becomes 'detest'.
'labour' becomes 'our' (I can't explain this - if you can you should give a lot more credence to this answer).
'detest' with half the letters taken is 'det'.
'det'+'our'='DETOUR'
'resulting in' is the link.
Can you help me to learn more?
(Other definitions for detour that I've seen before include "Go round an obstruction" , "Temporary roundabout way" , "Circuitous alternative to direct path" , "Deviate from planned route, go around" , "Indirect route" .)