Hand-cleaning bar (4)
I believe the answer is:
soap
'hand-cleaning bar' is the definition.
(I've seen this in another clue)
This is the entire clue.
(Other definitions for soap that I've seen before include "Cleansing substance" , "A cleansing sort of TV serial" , "Popular TV programme (which cleans?)" , "Cleaning substance - melodramatic TV or radio series" , "TV programme; cleanser" .)