Crossword Genius

Handcuff (7)

Ross

I think it could be either:

manacle

shackle

'handcuff' is the definition.
(synonyms)

This is the entire clue.

(Other definitions for manacle that I've seen before include "Curb" , "restricting at the cuff?" , "Fetter" , "Handcuff" , "Hand/ankle restraint" .)

I've seen this clue in The Guardian, the L.A. Times Daily, The Telegraph, the Universal, the Sydney Morning Herald, The Washington Post, the New York Times, the Evening Standard and the Newsday.com.
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