Handsome man not half in trouble (3)
I believe the answer is:
ado
'trouble' is the definition.
(thesaurus)
'handsome man not half' is the wordplay.
'handsome man' becomes 'adonis' (I've seen this before).
'not half' indicates taking half.
'adonis' with half the letters taken is 'ADO'.
'in' acts as a link.
(Other definitions for ado that I've seen before include "carry-on" , "'Much ... About Nothing, Shakespeare play (3)'" , "excitement" , "Fuss or bustle" , "flapping" .)