Handy part under which there is domination (5)
I believe the answer is:
thumb
'handy part' is the definition.
'thumb' can be an answer for 'part' (thumb is a kind of part). I am unsure of the 'handy' bit.
I can't explain the remainder of the clue.
Can you help me to learn more?
(Other definitions for thumb that I've seen before include "Travel by . . . . . - hitchhike" , "Try to get a lift" , "Hitch ride" , "Attempt to obtain a lift" , "One opposed to other manual workers" .)