Crossword Genius

Harass, trouble (6)

Ross

I believe the answer is:

plague

This clue is a double definition.

'harass' is the first definition.
(I know that harass can be written as plague)

'trouble' is the second definition.
(I know that plague is a type of calamity)

(Other definitions for plague that I've seen before include "Outbreak of a deadly disease, or infestation of pest like locusts" , "Large-scale illness" , "Contagious disease that spreads rapidly and kills many" , "Badger" , "fatal outbreak" .)

I've seen this clue in The Times.
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