Hardships (4)
'hardships' is the definition.
('rigor' can be a synonym of 'hardship')
This is all the clue.
'hardships' is the definition.
(ill is a kind of hardship)
This is the entire clue.
(Other definitions for ills that I've seen before include "complaints" , "Evils or sicknesses" , "they're troublesome" , "Misfortunes or maladies" , "Sicknesses or harms" .)