Harlem bar got around Prohibition (7)
I believe the answer is:
embargo
'prohibition' is the definition.
(I've seen this before)
'harlem bar got around' is the wordplay.
'around' indicates the answer is hidden within the clue.
'EMBARGO' is hidden in the letters of 'harlem bar got'.
(Other definitions for embargo that I've seen before include "Commercial break" , "Government trade ban" , "Ban on commerce - mob rage (anag)" , "Eg, Rambo? (anag)" , "Government order imposing a trade barrier" .)