Harry for Meghan? A looker mostly head over heels, being in Africa (5)
I believe the answer is:
hyena
'being in africa' is the definition.
(animal native to Africa)
'harry for meghan? a looker mostly head over heels' is the wordplay.
'harry for meghan?' becomes 'H' (Meghan calls Prince Harry 'H').
'a looker' becomes 'an eye' (eyes look at things).
'mostly' means to remove the last letter (most but not all of the word).
'head over heels' is a reversal indicator (in a down clue, letters flip upside down).
'aneye' with its final letter removed is 'aney'.
'aney' in reverse letter order is 'yena'.
'h'+'yena'='HYENA'
(Other definitions for hyena that I've seen before include "Carnivorous mammal" , "Dog-like carrion-feeding mammal" , "Wild mammal" , "Its howl sounds like laughter" , "African scavenger" .)