Harry's wrong holding hands (7)
I believe the answer is:
torment
'harry's' is the definition.
(thesaurus)
'wrong holding hands' is the wordplay.
'wrong' becomes 'tort' (legal term).
'holding' means one lot of letters goes inside another.
'hands' becomes 'men' ('men' can be a synonym of 'hands').
'tort' placed around 'men' is 'TORMENT'.
(Other definitions for torment that I've seen before include "Extreme mental or physical distress" , "Anguish" , "Pester or tease unmercifully" , "Physical or mental pain" , "More TNT (anag.)" .)