Harvest disease leads to making one unconscious (6,3)

I believe the answer is:

laying out

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'harvest disease leads to' is the definition.
I can't judge whether this definition defines the answer.

'one unconscious' is the wordplay.
'one' becomes 'laying' (I am not sure about this - if you are sure you should give a lot more credence to this answer).
'unconscious' becomes 'out' (similar in meaning).
'laying'+'out'='LAYING OUT'

'making' is the link.

Can you help me to learn more?

I've seen this clue in The Guardian.

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