Hate anise as, strangely, it produces a numbing effect (11)
I believe the answer is:
anaesthesia
'it produces a numbing effect' is the definition.
The definition suggests a singular noun which matches the answer.
'hate anise as strangely' is the wordplay.
'strangely' indicates anagramming the letters.
'hate'+'anise'+'as'='hateaniseas'
'hateaniseas' is an anagram of 'ANAESTHESIA'.
Can you help me to learn more?
(Other definitions for anaesthesia that I've seen before include "Drug-induced insensitivity to pain" , "Loss of feeling through administered drugs" , "Insensitivity to pain induced by drugs" .)