Hate extremely delicate examination (6)
I believe the answer is:
detest
'hate' is the definition.
('detest' can be a synonym of 'hate')
'extremely delicate examination' is the wordplay.
'extremely' says to hollow out the word (remove centre letters).
'examination' becomes 'test' ('test' can be a synonym of 'examination').
'delicate' with its middle removed is 'de'.
'de'+'test'='DETEST'
(Other definitions for detest that I've seen before include "Dislike heartily" , "Hate a lot" , "Greatly hate" , "Despise or loathe" , "Cordially laothe" .)