Have a holiday, and leave me alone (2,4)
I believe the answer is:
go away
I believe this is a double definition.
'have a holiday' is the first definition.
'leave me alone' is the second definition.
(phrase used to tell someone to leave you alone)
'and' acts as a link.
(Other definitions for go away that I've seen before include "Leave" , "Disappear" , "Scram" , "Push off" , "Depart" .)