Having acquired knowledge about home working (2,2)
I believe the answer is:
in on
'having acquired knowledge' is the definition.
I don't know anything about this answer so I cannot judge whether it can be defined by this definition.
'home working' is the wordplay.
'home' becomes 'in' ('he's home' can mean 'he's in').
'working' becomes 'on' (e.g. a machine is working or on).
'in'+'on'='IN ON'
'about' is the link.
Can you help me to learn more?
(Other definitions for in on that I've seen before include "Participating in - knowing about" , "Wise to" , "Aware of - being part of" , "Privy to" , "Aware of secret" .)