Having received audible jeer, escaped totally exhausted (8)
I believe the answer is:
frazzled
'totally exhausted' is the definition.
(frazzled means completely exhausted)
'having received audible jeer escaped' is the wordplay.
'having received' is an insertion indicator.
'audible jeer' becomes 'razz' (short for raspberry, as in blowing a raspberry).
'escaped' becomes 'fled' (I've seen this in another clue).
'razz' inserted within 'fled' is 'FRAZZLED'.
(Other definitions for frazzled that I've seen before include "Completely exhausted" , "Worn to rags or tatters, exhausted" .)