Having trouble, so off to Spain (2,1,4)
I believe the answer is:
in a spot
'having trouble' is the definition.
(I've seen this before)
'off to spain' is the wordplay.
'off' is an anagram indicator.
'to'+'spain'='tospain'
'tospain' with letters rearranged gives 'IN A SPOT'.
'so' acts as a link.
(Other definitions for in a spot that I've seen before include "having problems" , "Badly placed" , "Having trouble" , "Awkwardly situated (colloq.)" , "Facing difficulties" .)