He cooks with some panache, frequently (4)
I believe the answer is:
chef
'he cooks' is the definition.
'with some panache frequently' is the wordplay.
'with' indicates a hidden word.
'CHEF' is hidden in the letters of 'some panache frequently'.
(Other definitions for chef that I've seen before include "Chief male cook in restaurant" , "Professional cook" , "member of kitchen staff" , "Principal cook" , "Saucier" .)