He is going around and angry with this being homespun (8)
I believe the answer is:
handmade
'this being homespun' is the definition.
(thesaurus)
'he is going around and angry' is the wordplay.
'is going around' means one lot of letters goes inside another.
'angry' becomes 'mad' (similar in meaning).
'and'+'mad'='andmad'
'he' enclosing 'andmad' is 'HANDMADE'.
'with' acts as a link.
(Other definitions for handmade that I've seen before include "Produced with craftsmanship" , "Bespoke" , "E.g. like samplers" , "Personally developed" , "superior wear" .)