Head removed from serious figure (6)
I believe the answer is:
eighty
'figure' is the definition.
(I've seen this before)
'head removed from serious' is the wordplay.
'head removed from' means to remove the first letter.
'serious' becomes 'weighty' (synonyms).
'weighty' with its initial letter removed is 'EIGHTY'.
(Other definitions for eighty that I've seen before include "score less than a hundred" , "Figure" , "Around the World in - Days (Verne)" , "4 score" , "XXC" .)