Headed for the hills (4)
I believe the answer is:
fled
'headed for the hills' is the definition.
(I've seen this in another clue)
This is the entire clue.
(Other definitions for fled that I've seen before include "Female showed the way and escaped" , "Did a runner" , "Having run or hurried away" , "Left the field" , "Ran or hurried away" .)