Heads rolling in “hire and fire” will produce such anger (3)
I believe the answer is:
ire
'anger' is the definition.
(ire is intense rage)
I cannot understand how the remainder of the clue works.
Can you help me to learn more?
(Other definitions for ire that I've seen before include "Annoyance, vexation" , "Outrage" , "Intense anger" , "'Anger, wrath (3)'" , "Strong emotion" .)