Heart of the Indies, possibly (6)
I believe the answer is:
inside
'heart' is the definition.
(thesaurus)
'the indies possibly' is the wordplay.
'possibly' indicates anagramming the letters.
'indies' anagrammed gives 'INSIDE'.
'of' acts as a link.
(Other definitions for inside that I've seen before include "Enid is (anag) - within" , "confined" , "A sort of job" , "Privileged" , "Inner surface" .)