Heartless killjoy getting annoyed as comic speaks (6)
I believe the answer is:
jokily
'as comic speaks' is the definition.
(a comic might speak in a jokey way)
'heartless killjoy getting annoyed' is the wordplay.
'heartless' means to remove the middle letters.
'getting annoyed' indicates anagramming the letters.
'killjoy' with its centre taken out is 'kiljoy'.
'kiljoy' is an anagram of 'JOKILY'.
I've seen this clue in The Independent.
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