Heaven-bound American uncle entertaining European women inspired by Dionysus (7)
I believe the answer is:
maenads
'women inspired by dionysus' is the definition.
(a maenad was a worshipper of Dionysus)
'heaven-bound american uncle entertaining european' is the wordplay.
'heaven-bound' is a reversal indicator (in a down clue, words go up or 'to heaven').
'american uncle' becomes 'Sam' (Uncle Sam is a nickname for the USA).
'entertaining' indicates putting letters inside.
'european' becomes 'dane' (someone from Denmark).
'sam' enclosing 'dane' is 'sdaneam'.
'sdaneam' backwards is 'MAENADS'.
(Other definitions for maenads that I've seen before include "frenzied females!" , "Frenzied women" .)