Her best lead is lost then found again (2-11)
I believe the answer is:
re-established
'found again' is the definition.
(found can mean to establish)
'her best lead is lost' is the wordplay.
'lost' indicates an anagram.
'her'+'best'+'lead'+'is'='herbestleadis'
'herbestleadis' with letters rearranged gives 'RE-ESTABLISHED'.
'then' is the link.
I've seen this clue in The Guardian.
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