Her sin destroyed a holy place (6)
I believe the answer is:
shrine
'a holy place' is the definition.
(holy site dedicated to a particular person)
'her sin destroyed' is the wordplay.
'destroyed' indicates an anagram.
'her'+'sin'='hersin'
'hersin' with letters rearranged gives 'SHRINE'.
(Other definitions for shrine that I've seen before include "Place hallowed for special associations" , "Hallowed place associated with a sacred thing or person" , "Casket with holy relics" , "temple" , "here to pray?" .)