Her weapon was of no use in a manhunt (5)
I believe the answer is:
annie
'her' is the definition.
'weapon was of no use in a manhunt' is the wordplay.
I cannot really see how this works, but
'no' could be 'n' (common abbreviation) and 'n' is found within the answer.
'a' could be 'an' and 'an' is present in the answer.
This may be the basis of the clue (or it may be nonsense).
Can you help me to learn more?
(Other definitions for annie that I've seen before include "Cartoon strip orphan" , "Inane (anag) - girl (with a gun?)" , "musical movie" , "- Get your Gun, musical" , "Miss Laurie" .)