Her wit is enough to make one squirm! (6)
I believe the answer is:
writhe
'one squirm' is the definition.
(I've seen this in another clue)
'her wit is enough to' is the wordplay.
'her wit' anagrams to 'WRITHE'.
Though, I am not sure how this is indicated.
'make' is the link.
Can you help me to learn more?
(Other definitions for writhe that I've seen before include "Squirm in pain" , "It's painful moving" , "Struggle" , "worm" , "6, maybe in agony" .)