Heroine lost in blighted hope and rising trouble (7)
I believe the answer is:
ophelia
'heroine' is the definition.
(I have seen 'Tragic heroine' mean 'ophelia' so perhaps 'heroine' could also mean 'ophelia')
'blighted hope and rising trouble' is the wordplay.
'blighted' indicates an anagram (I've seen this in other clues).
'and' says to put letters next to each other.
'rising' says the letters should be written in reverse (going up in a down clue).
'trouble' becomes 'ail' (synonyms).
'ail' back-to-front is 'lia'.
'hope' is an anagram of 'ophe'.
'ophe'+'lia'='OPHELIA'
'lost in' acts as a link.
This may not be correct. Some or all of it may be part of another bit of the clue.
Can you help me to learn more?
(Other definitions for ophelia that I've seen before include "intended for prince?" , "Laertes' sister (Shak.)" , "She drowned dramatically" , "character of Skakespeare" , "Character in Hamlet" .)