He's unable to serve any longer (5)
I believe the answer is:
lifer
'he's unable to serve any longer' is the definition.
The answer is a person as well as being a singular noun. This is suggested by the definition.
This is the entire clue.
Can you help me to learn more?
(Other definitions for lifer that I've seen before include "Rifle (anag.)" , "Prisoner serving the maximum term" , "Person serving long sentence" , "One behind bars for ever" , "person given sizeable bird" .)