Hide ecstasy in panic (7)
I believe the answer is:
leather
'hide' is the definition.
(an animal hide)
'ecstasy in panic' is the wordplay.
'ecstasy' becomes 'E' (informal term for the drug).
'in' indicates putting letters inside.
'panic' becomes 'lather' (as in a phrase like 'in a lather').
'e' going within 'lather' is 'LEATHER'.
(Other definitions for leather that I've seen before include "Flog; hide" , "Dressed skin" , "Treated animal skin" , "Polishing cloth" , "Treated hide" .)