Hide family under Samaritan's roof (4)
I believe the answer is:
skin
'hide' is the definition.
(a hide is an animal skin)
'family under samaritan's roof' is the wordplay.
'family' becomes 'kin' (synonyms).
'under' says to put letters next to each other.
'roof' indicates taking the first letters (the letter at the top of the word).
The first letter of 'samaritans' is 's'.
'kin' put after 's' is 'SKIN'.
(Other definitions for skin that I've seen before include "External surface" , "coat" , "External membrane of body" , "Scrape, as the knee" , "Fell" .)