High cynical tone confused (11)
I believe the answer is:
anticyclone
'high' is the definition.
(thesaurus)
'cynical tone confused' is the wordplay.
'confused' indicates anagramming the letters.
'cynical'+'tone'='cynicaltone'
'cynicaltone' with letters rearranged gives 'ANTICYCLONE'.
(Other definitions for anticyclone that I've seen before include "High-pressure weather system" , "Swirl in the atmosphere" , "Circulating weather system" .)