High temperature? Totally (4)
I believe the answer is:
tall
'high' is the definition.
(similar in meaning)
'temperature? totally' is the wordplay.
'temperature?' becomes 't' (abbreviation).
'totally' becomes 'all'.
't'+'all'='TALL'
(Other definitions for tall that I've seen before include "High in stature" , "Remarkable" , "description of a giraffe?" , "Like giants" , "Higher than the average person" .)