Hinder male cleaner (9)
I believe the answer is:
detergent
'cleaner' is the definition.
(chemical that cleans)
'hinder male' is the wordplay.
'hinder' becomes 'deter' (I've seen this before).
'male' becomes 'gent' (gent is a kind of male).
'deter'+'gent'='DETERGENT'
(Other definitions for detergent that I've seen before include "Get tender (anag)" , "Cleaning product" , "Synthetic cleaning substance for washing machines" , "cleaner" , "Cleansing solvent" .)