His changes to the Bible upset God (5)
I believe the answer is:
shiva
'god' is the definition.
(Shiva is an example)
'his changes to the bible upset' is the wordplay.
'changes' indicates an anagram.
'to the bible' becomes 'av'.
'upset' says the letters should be written in reverse.
'av' in reverse letter order is 'va'.
'his' anagrammed gives 'shi'.
'shi'+'va'='SHIVA'
(Other definitions for shiva that I've seen before include "powerful deity" , "Hindu god, the destroyer" , "Jewish period of mourning" , "Destroyer goddess of Hinduism" , "Major Hindu god with third eye in middle of forehead" .)