Hit Charlie on cheek (4)
I believe the answer is:
clip
'hit' is the definition.
(thesaurus)
'charlie on cheek' is the wordplay.
'charlie' becomes 'c' (phonetic alphabet: alpha, bravo, charlie etc.).
'on' is a charade indicator (letters next to each other).
'cheek' becomes 'lip' (both can mean insolence or rudeness).
'c'+'lip'='CLIP'
(Other definitions for clip that I've seen before include "Film excerpt" , "Shorten" , "It can hold cartridges and hair" , "Piece of film etc" , "speed" .)