Holiday in desert? (5)
I believe the answer is:
leave
I believe this clue is a double definition.
'holiday' is the first definition.
(I've seen this before)
'desert?' is the second definition.
(desert can mean to leave or abandon)
'in' acts as a link.
(Other definitions for leave that I've seen before include "Something taken by those withdrawing" , "Pull out" , "Don't touch" , "Break" , "Insufficient foliage" .)