Holy person and general in disagreement (6)
I believe the answer is:
strife
'disagreement' is the definition.
(I have seen 'Bitter disagreement' mean 'strife' so perhaps 'disagreement' could also mean 'strife')
'holy person and general' is the wordplay.
'holy person' becomes 'st' (I've seen this in other clues).
'and' says to put letters next to each other.
'general' becomes 'rife' (I've seen this in other clues).
'st'+'rife'='STRIFE'
'in' is the link.
(Other definitions for strife that I've seen before include "Conflict, dispute" , "Bitter disagreement" , "Discord and friction" , "Refits (anag)" , "Heated discord" .)