Home from the East (4)
I believe the answer is:
seat
'home' is the definition.
(thesaurus)
'from the east' is the wordplay.
'from' indicates an anagram (from the letters).
'east' is an anagram of 'SEAT'.
(Other definitions for seat that I've seen before include "Chair, bench, or stool, say" , "Position (in parliament)" , "Take one and sit" , "Sitting place" , "pew?" .)