Home-grown new musical coming back (6)
I believe the answer is:
native
'home-grown' is the definition.
(similar in meaning)
'new musical coming back' is the wordplay.
'new' becomes 'n' (abbreviation as in New Testament NT).
'musical' becomes 'evita' (Andrew Lloyd Webber musical).
'coming back' is a reversal indicator.
'evita' back-to-front is 'ative'.
'n'+'ative'='NATIVE'
(Other definitions for native that I've seen before include "Indigenous, aboriginal" , "Endemic - aborigine" , "Local inhabitant" , "Of person, belonging by birth to place" , "Belonging to a particular place by birth" .)