Honoured with Nobel, nerd’s somehow not reading (8)
I believe the answer is:
ennobled
'honoured' is the definition.
(ennobling is a kind of honouring)
'nobel nerd's somehow not reading' is the wordplay.
I cannot really understand how this works, but
an anagram of 'nobel' is 'noble' which is within the answer.
The remaining letters 'end' is a valid word which might be clued in a way I don't see.
This explanation may well be incorrect...
'with' acts as a link.
(Other definitions for ennobled that I've seen before include "Dignified" , "Given peerage" , "Raised to the peerage in the UK" , "Got up to peer" , "Elevated to the peerage" .)