'Horrible Bosses' to occupy one's thoughts (6)
I believe the answer is:
obsess
'occupy one's thoughts' is the definition.
'horrible bosses' is the wordplay.
'horrible' indicates an anagram.
'bosses' anagrammed gives 'OBSESS'.
'to' is the link.
(Other definitions for obsess that I've seen before include "Be constantly talking about" , "Haunt - preoccupy" , "brood" , "Think only" , "Preoccupy completely" .)