Horrible pain sir? Take this (7)
I believe the answer is:
aspirin
'horrible pain sir? take this' is the definition.
The definition suggests a singular noun which matches the answer. I also know that 'pain' relates to this answer.
'horrible pain sir?' is the wordplay.
'horrible' indicates anagramming the letters.
'pain'+'sir'='painsir'
'painsir' is an anagram of 'ASPIRIN'.
Can you help me to learn more?
(Other definitions for aspirin that I've seen before include "Synthetic analgesic" , "Anodyne" , "answer to pain?" , "Analgesic over in Paris" , "Sip rain (anag.)" .)