Hotel guest trendies disturbed (8)
I believe the answer is:
resident
'hotel guest' is the definition.
(I've seen this before)
'trendies disturbed' is the wordplay.
'disturbed' is an anagram indicator.
'trendies' with letters rearranged gives 'RESIDENT'.
(Other definitions for resident that I've seen before include "Someone with a home" , "Local" , "One living in the place referred to" , "Dwelling in a place for some time" , "Liver" .)